Tumor mutational burden
id:
tumor-mutational-burden-251-16410125
title:
Tumor mutational burden
text:
Tumour mutational burden is a genetic characteristic of tumorous tissue that can be informative to cancer research and treatment. It is defined as the number of non-inherited mutations per million bases (Mb) of investigated genomic sequence, and its measurement has been enabled by next generation sequencing. High TMB and DNA damage repair mutations were discovered to be associated with superior clinical benefit from immune checkpoint blockade therapy by Timothy Chan and colleagues at the Memoria
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Tumor_mutational_burden
date created:
date modified:
2024-02-15T21:17:21Z
main entity:
{"identifier":"Q105987191","url":"https://www.wikidata.org/entity/Q105987191"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/39/TMB-Antigen_Association.jpg","width":720,"height":504}
fields total:
13
integrity:
14