Death-inducing signaling complex
id:
death-inducing-signaling-complex-274-5114892
title:
Death-inducing signaling complex
text:
The death-inducing signaling complex or DISC is a multi-protein complex formed by members of the death receptor family of apoptosis-inducing cellular receptors. A typical example is FasR, which forms the DISC upon trimerization as a result of its ligand (FasL) binding. The DISC is composed of the death receptor, FADD, and caspase 8. It transduces a downstream signal cascade resulting in apoptosis.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Death-inducing_signaling_complex
date created:
date modified:
2023-08-18T08:12:10Z
main entity:
{"identifier":"Q5247052","url":"https://www.wikidata.org/entity/Q5247052"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/20/Fas_signaling.jpg","width":1024,"height":768}
fields total:
13
integrity:
14