Apoptotic DNA fragmentation
id:
apoptotic-dna-fragmentation-254-14536498
title:
Apoptotic DNA fragmentation
text:
Apoptotic DNA fragmentation is a key feature of apoptosis, a type of programmed cell death. Apoptosis is characterized by the activation of endogenous endonucleases, particularly the caspase-3 activated DNase (CAD), with subsequent cleavage of nuclear DNA into internucleosomal fragments of roughly 180 base pairs (bp) and multiples thereof (360, 540 etc.). The apoptotic DNA fragmentation is being used as a marker of apoptosis and for identification of apoptotic cells either via the DNA laddering
brand slug:
wiki
category slug:
encyclopedia
description:
Cleavage of DNA into tiny pieces during apoptosis
original url:
https://en.wikipedia.org/wiki/Apoptotic_DNA_fragmentation
date created:
date modified:
2024-02-05T04:09:16Z
main entity:
{"identifier":"Q4780527","url":"https://www.wikidata.org/entity/Q4780527"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/75/Apoptotic_DNA_Laddering.png","width":178,"height":193}
fields total:
13
integrity:
15