Zebularine
id:
zebularine-265-8333931
title:
Zebularine
text:
Zebularine is a nucleoside analog of cytidine. It is a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo. In a small study of mice with a defective Adenomatous polyposis coli gene, oral administration of zebularine to males had no effect on the overall methylation of DNA or the number of polyps, but in females the average number of polyps was reduced from 58
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Zebularine
date created:
date modified:
2024-03-06T21:59:34Z
main entity:
{"identifier":"Q8068322","url":"https://www.wikidata.org/entity/Q8068322"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e0/Zebularine.svg","width":512,"height":317}
fields total:
13
integrity:
15