Xorphanol
id:
xorphanol-238-7986343
title:
Xorphanol
text:
Xorphanol (INN) (developmental code name TR-5379 or TR-5379M), also known as xorphanol mesylate (USAN), is an opioid analgesic of the morphinan family that was never marketed. Xorphanol is a mixed agonist–antagonist of opioid receptors, acting preferentially as a high-efficacy partial agonist/near-full agonist of the κ-opioid receptor (Ki = 0.4 nM; EC50 = 3.3 nM; Imax = 49%; IA = 0.84) and to a lesser extent as a partial agonist of the μ-opioid receptor (Ki = 0.25 nM; IC50 = 3.4 nM; Imax = 29%)
brand slug:
wiki
category slug:
encyclopedia
description:
Opioid analgesic
original url:
https://en.wikipedia.org/wiki/Xorphanol
date created:
date modified:
2024-02-05T17:44:36Z
main entity:
{"identifier":"Q8044946","url":"https://www.wikidata.org/entity/Q8044946"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/1/1f/Xorphanol.svg","width":620,"height":453}
fields total:
13
integrity:
15