WAY-161503
id:
way-161503-281-16300799
title:
WAY-161503
text:
WAY-161503 is a full agonist of 5-HT2C receptors (Ki = 3.3 nM for displacement of DOI), ~6-fold less potent at 5-HT2A receptors (Ki = 18 nM) and 20-fold less potent at 5-HT2B receptors (Ki = 60 nM). In functional studies, it stimulates calcium mobilization coupled to 5-HT2C, 5-HT2B, and 5-HT2A receptors with EC50 values of 0.8, 1.8, and 7 nM, respectively. WAY-161503 has been reported to produce dose-dependent decreases in food intake in 24-hour fasted normal Sprague-Dawley rats, diet-induced ob
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/WAY-161503
date created:
date modified:
2022-11-08T19:31:47Z
main entity:
{"identifier":"Q7946880","url":"https://www.wikidata.org/entity/Q7946880"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/5c/WAY-161503.svg","width":512,"height":356}
fields total:
13
integrity:
15