Vorsetuzumab mafodotin
id:
vorsetuzumab-mafodotin-233-8108916
title:
Vorsetuzumab mafodotin
text:
Vorsetuzumab mafodotin (SGN-75) is an antibody-drug conjugate (ADC) directed to the protein CD70 designed for the treatment of cancer. It is a humanized monoclonal antibody, vorsetuzumab, conjugated with noncleavable monomethyl auristatin F (MMAF), a cytotoxic agent. This drug was developed by Seattle Genetics, Inc. The drug completed phase I clinical trials for renal cell carcinoma, but development was discontinued in 2013.
No reason was given but SG plan to start clinical trials of SGN-CD70A i
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Vorsetuzumab_mafodotin
date created:
date modified:
2024-01-01T00:11:57Z
main entity:
{"identifier":"Q7941885","url":"https://www.wikidata.org/entity/Q7941885"}
image:
fields total:
13
integrity:
14