VapBC
id:
vapbc-271-162958
title:
VapBC
text:
VapBC is the largest family of type II toxin-antitoxin system genetic loci in prokaryotes. VapBC operons consist of two genes: VapC encodes a toxic PilT N-terminus (PIN) domain, and VapB encodes a matching antitoxin. The toxins in this family are thought to perform RNA cleavage, which is inhibited by the co-expression of the antitoxin, in a manner analogous to a poison and antidote. First discovered in 1992, vapBC loci are now thought make up around 37–42% of all type II toxin-antitoxin systems.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/VapBC
date created:
date modified:
2023-11-28T00:14:24Z
main entity:
{"identifier":"Q7915304","url":"https://www.wikidata.org/entity/Q7915304"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/98/PDB_1o4w_EBI.jpg","width":442,"height":304}
fields total:
13
integrity:
14