Ure2 internal ribosome entry site (IRES)

id: ure2-internal-ribosome-entry-site-ires-310-14147392
title: Ure2 internal ribosome entry site (IRES)
text: In molecular biology, the Ure2 internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of Ure2. It allows 5' cap- and eIF4E-independent translation of an N-terminally truncated form of Ure2. This truncated form lacks the prion-forming domain. It is a 104 nucleotide region, smaller than most viral IRES elements, which forms a stem-loop structure. EIF2A represses this IRES resulting in an inhibition of translation of the N-terminally truncated Ure2.
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Ure2_internal_ribosome_entry_site_(IRES)
date created:
date modified: 2024-02-23T01:27:42Z
main entity: {"identifier":"Q17130580","url":"https://www.wikidata.org/entity/Q17130580"}
image:
fields total: 13
integrity: 13

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