Upstream open reading frame
id:
upstream-open-reading-frame-268-12786520
title:
Upstream open reading frame
text:
An upstream open reading frame (uORF) is an open reading frame (ORF) within the 5' untranslated region (5'UTR) of an mRNA. uORFs can regulate eukaryotic gene expression. Translation of the uORF typically inhibits downstream expression of the primary ORF. However, in some genes such as yeast GCN4, translation of specific uORFs may increase translation of the main ORF. In bacteria, uORFs are called leader peptides and were originally discovered on the basis of their impact on the regulation of gen
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Upstream_open_reading_frame
date created:
date modified:
2024-01-18T22:19:11Z
main entity:
{"identifier":"Q7899328","url":"https://www.wikidata.org/entity/Q7899328"}
image:
fields total:
13
integrity:
13