UBR2
id:
ubr2-319-12904179
title:
UBR2
text:
E3 ubiquitin-protein ligase UBR2 is an enzyme that in humans is encoded by the UBR2 gene. Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.[supplied by OMIM]
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/UBR2
date created:
date modified:
2023-03-03T23:37:30Z
main entity:
{"identifier":"Q18037076","url":"https://www.wikidata.org/entity/Q18037076"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/ea/Protein_UBR2_PDB_3NY2.png","width":1200,"height":1000}
fields total:
13
integrity:
15