U1A polyadenylation inhibition element (PIE)

id: u1a-polyadenylation-inhibition-element-pie-305-14600622
title: U1A polyadenylation inhibition element (PIE)
text: The U1A polyadenylation inhibition element (PIE) is an RNA element which is responsible for the regulation of the length of the polyA tail of the U1A protein pre-mRNA. The PIE is located in the U1A mRNA 3' UTR. PIE adopts a U-shaped structure, with binding sites for a single U1A protein at each bend and when complexed with the two proteins it blocks activity of poly(A) polymerase (PAP), and inhibits its activity.
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/U1A_polyadenylation_inhibition_element_(PIE)
date created:
date modified: 2022-01-16T17:50:00Z
main entity: {"identifier":"Q7863578","url":"https://www.wikidata.org/entity/Q7863578"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/4b/RF00460.jpg","width":452,"height":452}
fields total: 13
integrity: 14

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