Type II topoisomerase
id:
type-ii-topoisomerase-213-2687774
title:
Type II topoisomerase
text:
Type II topoisomerases are topoisomerases that cut both strands of the DNA helix simultaneously in order to manage DNA tangles and supercoils. They use the hydrolysis of ATP, unlike Type I topoisomerase. In this process, these enzymes change the linking number of circular DNA by ±2. Topoisomerases are ubiquitous enzymes, found in all living organisms. In animals, topoisomerase II is a chemotherapy target. In prokaryotes, gyrase is an antibacterial target. Indeed, these enzymes are of interest fo
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Type_II_topoisomerase
date created:
2007-01-19T02:32:08Z
date modified:
2024-09-12T09:31:36Z
main entity:
{"identifier":"Q411991","url":"https://www.wikidata.org/entity/Q411991"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/bb/Gyr.PNG","width":447,"height":445}
fields total:
13
integrity:
15