Tumor necrosis factor

id: tumor-necrosis-factor-184-8286628
title: Tumor necrosis factor
text: Tumor necrosis factor (TNF), formerly known as TNF-α, is an inflammatory protein and a principal mediator of the innate immune response. TNF is produced primarily by macrophages in response to antigens, and activates inflammatory pathways through its two receptors, TNFR1 and TNFR2. It is a member of the tumor necrosis factor superfamily, a family of type II transmembrane proteins that function as cytokines. Excess production of TNF plays a critical role in the pathology of several inflammatory d
brand slug: wiki
category slug: encyclopedia
description: Protein
original url: https://en.wikipedia.org/wiki/Tumor_necrosis_factor
date created: 2003-06-05T22:08:47Z
date modified: 2024-09-07T08:43:31Z
main entity: {"identifier":"Q21173843","url":"https://www.wikidata.org/entity/Q21173843"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/3b/TNFa_Crystal_Structure.rsh.png","width":740,"height":750}
fields total: 13
integrity: 16

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