Tuberous sclerosis complex tumor suppressors
id:
tuberous-sclerosis-complex-tumor-suppressors-263-9364637
title:
Tuberous sclerosis complex tumor suppressors
text:
Tuberous sclerosis complex (TSC) tumor suppressors form the TSC1-TSC2 molecular complex. Under poor growth conditions the TSC1-TSC2 complex limits cell growth. A key promoter of cell growth, mTORC1, is inhibited by the tuberous sclerosis complex. Insulin activates mTORC1 and causes dissociation of TSC from the surface of lysosomes. Resistance to ischemia-reperfusion injury by protein restriction is mediated by activation of the tuberous sclerosis complex.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Tuberous_sclerosis_complex_tumor_suppressors
date created:
date modified:
2022-07-03T15:34:59Z
main entity:
{"identifier":"Q25098581","url":"https://www.wikidata.org/entity/Q25098581"}
image:
fields total:
13
integrity:
13