TPA-023

id: tpa-023-180-14173089
title: TPA-023
text: TPA-023 (MK-0777) is an anxiolytic drug with a novel chemical structure, which is used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. It is a mixed, subtype-selective ligand of the benzodiazepine site of α1, α2, α3, and α5-containing GABAA receptors, where it acts as a partial agonist at benzodiazepine sites of the α2 and α3-containing subtypes, but as a silent antagonist at α1 and α5-conta
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/TPA-023
date created: 2008-08-08T08:14:47Z
date modified: 2024-09-05T14:12:34Z
main entity: {"identifier":"Q7671096","url":"https://www.wikidata.org/entity/Q7671096"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/02/TPA-023.png","width":426,"height":486}
fields total: 13
integrity: 16

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