TOR1AIP1

id: tor1aip1-249-14021195
title: TOR1AIP1
text: Torsin-1A-interacting protein 1 is a protein that in humans is encoded by the TOR1AIP1 gene. More commonly known as lamina associated polypeptide 1 (LAP1), it is a type II integral membrane protein that resides in the inner nuclear membrane. The luminal domain of LAP1 interacts with Torsin A and is necessary for the ATPase activity of Torsin A. LAP1 plays a critical role in skeletal and heart muscle. Mutations in TOR1AIP1 have been linked to muscular dystrophy and cardiomyopathy. It's deletion f
brand slug: wiki
category slug: encyclopedia
description: Protein-coding gene in the species Homo sapiens
original url: https://en.wikipedia.org/wiki/TOR1AIP1
date created:
date modified: 2022-10-11T18:39:21Z
main entity: {"identifier":"Q18038104","url":"https://www.wikidata.org/entity/Q18038104"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/d/d6/Ideogram_human_chromosome_1.svg","width":474,"height":189}
fields total: 13
integrity: 15

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