Topoisomerase inhibitor
id:
topoisomerase-inhibitor-188-5754532
title:
Topoisomerase inhibitor
text:
Topoisomerase inhibitors are chemical compounds that block the action of topoisomerases, which are broken into two broad subtypes: type I topoisomerases (TopI) and type II topoisomerases (TopII). Topoisomerase plays important roles in cellular reproduction and DNA organization, as they mediate the cleavage of single and double stranded DNA to relax supercoils, untangle catenanes, and condense chromosomes in eukaryotic cells. Topoisomerase inhibitors influence these essential cellular processes.
brand slug:
wiki
category slug:
encyclopedia
description:
Compounds that inhibit the activity of DNA topoisomerases
original url:
https://en.wikipedia.org/wiki/Topoisomerase_inhibitor
date created:
2006-08-25T18:11:00Z
date modified:
2024-09-08T19:07:36Z
main entity:
{"identifier":"Q281044","url":"https://www.wikidata.org/entity/Q281044"}
image:
fields total:
13
integrity:
15