Topoisomerase
id:
topoisomerase-301-7684591
title:
Topoisomerase
text:
DNA topoisomerases are enzymes that catalyze changes in the topological state of DNA, interconverting relaxed and supercoiled forms, linked (catenated) and unlinked species, and knotted and unknotted DNA. Topological issues in DNA arise due to the intertwined nature of its double-helical structure, which, for example, can lead to overwinding of the DNA duplex during DNA replication and transcription. If left unchanged, this torsion would eventually stop the DNA or RNA polymerases involved in the
brand slug:
wiki
category slug:
encyclopedia
description:
Class of enzymes
original url:
https://en.wikipedia.org/wiki/Topoisomerase
date created:
date modified:
2023-12-11T00:11:41Z
main entity:
{"identifier":"Q407828","url":"https://www.wikidata.org/entity/Q407828"}
image:
fields total:
13
integrity:
14