TNK2
id:
tnk2-293-14745639
title:
TNK2
text:
Activated CDC42 kinase 1, also known as ACK1, is an enzyme that in humans is encoded by the TNK2 gene. TNK2 gene encodes a non-receptor tyrosine kinase, ACK1, that binds to multiple receptor tyrosine kinases e.g. EGFR, MERTK, AXL, HER2 and insulin receptor (IR). ACK1 also interacts with Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/TNK2
date created:
date modified:
2023-11-07T21:43:06Z
main entity:
{"identifier":"Q18035104","url":"https://www.wikidata.org/entity/Q18035104"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/44/Protein_TNK2_PDB_1cf4.png","width":890,"height":792}
fields total:
13
integrity:
15