TLN1
id:
tln1-289-17025385
title:
TLN1
text:
Talin-1 is a protein that in humans is encoded by the TLN1 gene. Talin-1 is ubiquitously expressed, and is localized to costamere structures in cardiac and skeletal muscle cells, and to focal adhesions in smooth muscle and non-muscle cells. Talin-1 functions to mediate cell-cell adhesion via the linkage of integrins to the actin cytoskeleton and in the activation of integrins. Altered expression of talin-1 has been observed in patients with heart failure, however no mutations in TLN1 have been l
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/TLN1
date created:
date modified:
2024-01-13T12:02:22Z
main entity:
{"identifier":"Q18032012","url":"https://www.wikidata.org/entity/Q18032012"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/95/Protein_TLN1_PDB_1mix.png","width":1055,"height":715}
fields total:
13
integrity:
15