Tight junction protein ZO-1

id: tight-junction-protein-zo-1-182-7969320
title: Tight junction protein ZO-1
text: Tight junction protein ZO-1 also known as Zonula Occludens-1 (ZO-1), is a 220-kD peripheral membrane protein that is encoded by the TJP1 gene in humans. It belongs to the family of zonula occludens proteins, which are tight junction-associated proteins and of which, ZO-1 is the first to be cloned. It was first isolated in 1986 by Stevenson and Goodenough using a monoclonal antibody raised in rodent liver to recognise a 225-kD polypeptide in whole liver homogenates and in tight junction-enriched
brand slug: wiki
category slug: encyclopedia
description: Protein found in humans
original url: https://en.wikipedia.org/wiki/Tight_junction_protein_ZO-1
date created: 2007-11-07T08:37:24Z
date modified: 2024-09-06T12:25:09Z
main entity: {"identifier":"Q18031999","url":"https://www.wikidata.org/entity/Q18031999"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/fe/Protein_TJP1_PDB_2h2b.png","width":647,"height":537}
fields total: 13
integrity: 16

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