Thiopurine
id:
thiopurine-324-48726
title:
Thiopurine
text:
The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders, and organ transplant recipients. Metabolism is catalyzed by S-methyltransferase and nudix hydrolase 15 (NUDT15). Litigation over patents covering diagnostic kits to monitor the dosing of these drugs led to a US Supreme Court case, Mayo Collaborative Services v. Prometheus Laboratories, Inc. that dramatically changed the nature of patent law in the United States.
brand slug:
wiki
category slug:
encyclopedia
description:
Class of chemical compounds
original url:
https://en.wikipedia.org/wiki/Thiopurine
date created:
date modified:
2023-12-24T08:09:58Z
main entity:
{"identifier":"Q3991665","url":"https://www.wikidata.org/entity/Q3991665"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/07/Tioguanine.svg","width":500,"height":422}
fields total:
13
integrity:
15