Thenoyltrifluoroacetone
id:
thenoyltrifluoroacetone-224-1607307
title:
Thenoyltrifluoroacetone
text:
Thenoyltrifluoroacetone, C8H5F3O2S, is a chemical compound used pharmacologically as a chelating agent. It is an inhibitor of cellular respiration by blocking the respiratory chain at complex II. Perhaps the first report of TTFA as an inhibitor of respiration was by A. L. Tappel in 1960. Tappel had the (erroneous) idea that inhibitors like antimycin and alkyl hydroxyquinoline-N-oxide might work by chelating iron in the hydrophobic milieu of respiratory membrane proteins, so he tested a series of
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Thenoyltrifluoroacetone
date created:
2008-07-17T14:47:25Z
date modified:
2024-09-14T08:17:50Z
main entity:
{"identifier":"Q5933755","url":"https://www.wikidata.org/entity/Q5933755"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/2d/Thenoyltrifluoroacetone-2D-skeletal.png","width":1100,"height":586}
fields total:
13
integrity:
16