Tesaglitazar
id:
tesaglitazar-298-3894942
title:
Tesaglitazar
text:
Tesaglitazar is a dual peroxisome proliferator-activated receptor agonist with affinity to PPARα and PPARγ, proposed for the management of type 2 diabetes. The drug had completed several phase III clinical trials, however in May, 2006 AstraZeneca announced that it had discontinued further development. Cardiac toxicity of tesaglitazar is related to mitochondrial toxicity caused by decrease in PPARγ coactivator 1-α and sirtuin 1 (SIRT1).
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Tesaglitazar
date created:
date modified:
2023-08-13T12:15:12Z
main entity:
{"identifier":"Q7705411","url":"https://www.wikidata.org/entity/Q7705411"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/89/Tesaglitazar_free_acid.png","width":844,"height":276}
fields total:
13
integrity:
15