Teplizumab
id:
teplizumab-279-15681788
title:
Teplizumab
text:
Teplizumab, sold under the brand name Tzield, is a humanized anti-CD3 monoclonal antibody that is the first approved treatment indicated to delay the onset of stage 3 type 1 diabetes (T1D) in people with stage 2 T1D. The Fc region of this antibody has been engineered to have Fc receptor non-binding (FNB) properties. The mechanisms of action of teplizumab appear to involve weak agonistic activity on signaling via the T cell receptor-CD3 complex associated with the development of anergy, unrespons
brand slug:
wiki
category slug:
encyclopedia
description:
Monoclonal antibody
original url:
https://en.wikipedia.org/wiki/Teplizumab
date created:
date modified:
2024-01-14T07:05:59Z
main entity:
{"identifier":"Q7701358","url":"https://www.wikidata.org/entity/Q7701358"}
image:
fields total:
13
integrity:
14