TBC1D4
id:
tbc1d4-263-6654000
title:
TBC1D4
text:
AS160, which was originally known as TBC1 domain family member 4 (TBC1D4), is a Rab GTPase-activating protein that in humans is encoded by the TBC1D4 gene. The 160 kD protein product was first discovered in a screen for novel substrates of the serine-threonine kinase Akt2, which phosphorylates AS160 at Thr-642 and Ser-588 after insulin stimulation. Insulin stimulation of fat and muscle cells results in translocation of the glucose transporter GLUT4 to the plasma membrane, and this translocation
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/TBC1D4
date created:
date modified:
2023-03-04T01:33:09Z
main entity:
{"identifier":"Q18034838","url":"https://www.wikidata.org/entity/Q18034838"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/89/Ideogram_human_chromosome_13.svg","width":474,"height":189}
fields total:
13
integrity:
15