T-cell receptor excision circles
id:
t-cell-receptor-excision-circles-296-1308556
title:
T-cell receptor excision circles
text:
T-cell receptor excision circles (TRECs) are small circles of DNA created in T-cells during their passage through the thymus as they rearrange their TCR genes. Their presence indicates maturation of T cells;
TRECs are reduced in SCID. Signal joint T-cell receptor excision circles (sjTRECs) might be used as a way to test the age of the individual from a blood sample. The detection of sjTRECs can be further used as a diagnostic tool to monitor the thymic output.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/T-cell_receptor_excision_circles
date created:
date modified:
2024-01-12T18:45:51Z
main entity:
{"identifier":"Q7667898","url":"https://www.wikidata.org/entity/Q7667898"}
image:
fields total:
13
integrity:
13