Synthesis-dependent strand annealing
id:
synthesis-dependent-strand-annealing-258-6812767
title:
Synthesis-dependent strand annealing
text:
Synthesis-dependent strand annealing (SDSA) is a major mechanism of homology-directed repair of DNA double-strand breaks (DSBs). Although many of the features of SDSA were first suggested in 1976, the double-Holliday junction model proposed in 1983 was favored by many researchers. In 1994, studies of double-strand gap repair in Drosophila were found to be incompatible with the double-Holliday junction model, leading researchers to propose a model they called synthesis-dependent strand annealing.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Synthesis-dependent_strand_annealing
date created:
date modified:
2024-03-18T13:14:01Z
main entity:
{"identifier":"Q7662703","url":"https://www.wikidata.org/entity/Q7662703"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/6d/Homologous_Recombination.jpg","width":393,"height":470}
fields total:
13
integrity:
14