STAG2
id:
stag2-288-14671454
title:
STAG2
text:
Cohesin subunit SA-2 (SA2) is a protein that in humans is encoded by the STAG2 gene. SA2 is a subunit of the Cohesin complex which mediates sister chromatid cohesion, homologous recombination and DNA looping. In somatic cells cohesin is formed of SMC3, SMC1, RAD21 and either SA1 or SA2 whereas in meiosis, cohesin is formed of SMC3, SMC1B, REC8 and SA3. STAG2 is frequently mutated in a range of cancers and several other disorders.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in humans
original url:
https://en.wikipedia.org/wiki/STAG2
date created:
date modified:
2023-12-01T05:06:38Z
main entity:
{"identifier":"Q18035633","url":"https://www.wikidata.org/entity/Q18035633"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/61/Structure_of_SA2_%28blue%29_and_RAD21_%28green%29_%28PDB_4PK7%29.png","width":1762,"height":1188}
fields total:
13
integrity:
15