SPRTN

id: sprtn-266-10373461
title: SPRTN
text: Spartan (SPRTN) is a protein that in humans is encoded by the SPRTN gene. It is involved in DNA repair. Ruijs-Aalfs syndrome is an autosomal recessive genetic disorder. Characteristics of this disorder are features of premature aging, chromosome instability and development of hepatocellular carcinoma. Ruijs-Aalfs syndrome arises as a result of mutations in the SPRTN gene that encodes a metalloproteinase employed in the repair of protein-linked DNA breaks.
brand slug: wiki
category slug: encyclopedia
description: Protein-coding gene in the species Homo sapiens
original url: https://en.wikipedia.org/wiki/SPRTN
date created:
date modified: 2022-04-08T20:14:38Z
main entity: {"identifier":"Q18047333","url":"https://www.wikidata.org/entity/Q18047333"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/d/d6/Ideogram_human_chromosome_1.svg","width":474,"height":189}
fields total: 13
integrity: 15

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