Spindle checkpoint

id: spindle-checkpoint-168-3372981
title: Spindle checkpoint
text: The spindle checkpoint, also known as the metaphase-to-anaphase transition, the spindle assembly checkpoint (SAC), the metaphase checkpoint, or the mitotic checkpoint, is a cell cycle checkpoint during metaphase of mitosis or meiosis that prevents the separation of the duplicated chromosomes (anaphase) until each chromosome is properly attached to the spindle. To achieve proper segregation, the two kinetochores on the sister chromatids must be attached to opposite spindle poles. Only this patter
brand slug: wiki
category slug: encyclopedia
description: Cell cycle checkpoint
original url: https://en.wikipedia.org/wiki/Spindle_checkpoint
date created: 2004-09-18T18:04:41Z
date modified: 2024-08-31T07:11:35Z
main entity: {"identifier":"Q9064829","url":"https://www.wikidata.org/entity/Q9064829"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e0/Cell_Cycle_2-2.svg","width":748,"height":764}
fields total: 13
integrity: 16

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