SPG20
id:
spg20-324-2122250
title:
SPG20
text:
Spartin is a protein that in humans is encoded by the SPG20 gene. This gene encodes a protein that contains a MIT domain. This protein may be involved in endosomal trafficking, microtubule dynamics, or both functions. Spartin loss has been associated to mitochondrial dysfunction, impaired complex I activity and altered pyruvate metabolism. Frameshift mutations associated with this gene cause autosomal recessive spastic paraplegia 20.
Troyer syndrome (SPG20) is a complicated type of hereditary sp
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/SPG20
date created:
date modified:
2024-01-04T09:18:50Z
main entity:
{"identifier":"Q18036731","url":"https://www.wikidata.org/entity/Q18036731"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/63/Protein_SPG20_PDB_2dl1.png","width":451,"height":395}
fields total:
13
integrity:
15