SPEF2
id:
spef2-313-191392
title:
SPEF2
text:
Sperm flagellar protein 2 is a protein that in humans is encoded by the SPEF2 gene. SPEF2 plays an important role in spermatogenesis and flagellar assembly. SPEF2 is expressed in all ciliated cells and is required for cilia function. Sperm contain cilia, and a mutation in the SPEF2 gene can cause male infertility due to immobile sperm. In a pig animal model, a SPEF2 mutation affects the sperm tail development. And a loss of function mutation in SPEF2 in mice causes the big giant head phenotype.
brand slug:
wiki
category slug:
encyclopedia
description:
Gene
original url:
https://en.wikipedia.org/wiki/SPEF2
date created:
date modified:
2022-10-17T09:54:38Z
main entity:
{"identifier":"Q11868650","url":"https://www.wikidata.org/entity/Q11868650"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/61/Ideogram_human_chromosome_5.svg","width":500,"height":200}
fields total:
13
integrity:
15