Sodium-hydrogen exchange regulatory cofactor 2
id:
sodium-hydrogen-exchange-regulatory-cofactor-2-235-17192050
title:
Sodium-hydrogen exchange regulatory cofactor 2
text:
Sodium-hydrogen exchange regulatory cofactor NHE-RF2 (NHERF-2) also known as tyrosine kinase activator protein 1 (TKA-1) or SRY-interacting protein 1 (SIP-1) is a protein that in humans is encoded by the SLC9A3R2 gene. NHERF-2 is a scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. It is necessary for cAMP-mediated phosphorylation and inhibition
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/Sodium-hydrogen_exchange_regulatory_cofactor_2
date created:
date modified:
2023-12-28T06:46:45Z
main entity:
{"identifier":"Q18034020","url":"https://www.wikidata.org/entity/Q18034020"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e9/Protein_SLC9A3R2_PDB_2he4.png","width":846,"height":656}
fields total:
13
integrity:
15