Smoothened
id:
smoothened-291-16906683
title:
Smoothened
text:
Smoothened is a protein that in humans is encoded by the SMO gene. Smoothened is a Class Frizzled G protein-coupled receptor that is a component of the hedgehog signaling pathway and is conserved from flies to humans. It is the molecular target of the natural teratogen cyclopamine. It also is the target of vismodegib, the first hedgehog pathway inhibitor to be approved by the U.S. Food and Drug Administration (FDA). Smoothened (Smo) is a key transmembrane protein that is a key component of the h
brand slug:
wiki
category slug:
encyclopedia
description:
Gene found in humans and other animals
original url:
https://en.wikipedia.org/wiki/Smoothened
date created:
date modified:
2024-03-17T16:24:22Z
main entity:
{"identifier":"Q18031607","url":"https://www.wikidata.org/entity/Q18031607"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/99/Ideogram_human_chromosome_7.svg","width":474,"height":189}
fields total:
13
integrity:
15