SKI protein
id:
ski-protein-203-1995763
title:
SKI protein
text:
The SKI protein is a nuclear proto-oncogene that is associated with tumors at high cellular concentrations. SKI has been shown to interfere with normal cellular functioning by both directly impeding expression of certain genes inside the nucleus of the cell as well as disrupting signaling proteins that activate genes. SKI negatively regulates transforming growth factor-beta (TGF-beta) by directly interacting with Smads and repressing the transcription of TGF-beta responsive genes. This has been
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/SKI_protein
date created:
date modified:
2023-12-22T01:54:28Z
main entity:
{"identifier":"Q14913261","url":"https://www.wikidata.org/entity/Q14913261"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/ad/Protein_SKI_PDB_1mr1.png","width":848,"height":562}
fields total:
13
integrity:
15