Signal peptidase
id:
signal-peptidase-294-6092716
title:
Signal peptidase
text:
Signal peptidases are enzymes that convert secretory and some membrane proteins to their mature or pro forms by cleaving their signal peptides from their N-termini. Signal peptidases were initially observed in endoplasmic reticulum (ER)-derived membrane fractions isolated from mouse myeloma cells. The key observation by César Milstein and colleagues was that immunoglobulin light chains were produced in a higher molecular weight form, which became processed by the ER membrane fraction. This findi
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Signal_peptidase
date created:
date modified:
2023-08-26T15:49:43Z
main entity:
{"identifier":"Q7512720","url":"https://www.wikidata.org/entity/Q7512720"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/04/SignalPeptidaseComplex.jpg","width":704,"height":593}
fields total:
13
integrity:
14