Sigma-1 receptor
id:
sigma-1-receptor-161-5322365
title:
Sigma-1 receptor
text:
The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the σ1 receptor is encoded by the SIGMAR1 gene. The σ1 receptor is a transmembrane protein expressed in many different tissue types. It is particularly concentrated in certain regions of the central nervous system. It has been implicated in several phenomena, including cardiovascular function, schizophrenia,
brand slug:
wiki
category slug:
encyclopedia
description:
Chaperone protein
original url:
https://en.wikipedia.org/wiki/Sigma-1_receptor
date created:
2007-01-09T08:09:23Z
date modified:
2024-08-27T02:18:54Z
main entity:
{"identifier":"Q408572","url":"https://www.wikidata.org/entity/Q408572"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/4c/Sigma-1_receptor_PDB_5hk2_Top.png","width":2000,"height":2000}
fields total:
13
integrity:
16