Shelterin
id:
shelterin-180-457647
title:
Shelterin
text:
Shelterin is a protein complex known to protect telomeres in many eukaryotes from DNA repair mechanisms, as well as to regulate telomerase activity. In mammals and other vertebrates, telomeric DNA consists of repeating double-stranded 5'-TTAGGG-3' (G-strand) sequences along with the 3'-AATCCC-5' (C-strand) complement, ending with a 50-400 nucleotide 3' (G-strand) overhang. Much of the final double-stranded portion of the telomere forms a T-loop (Telomere-loop) that is invaded by the 3' (G-strand
brand slug:
wiki
category slug:
encyclopedia
description:
Protein complex serving as a telomere cap
original url:
https://en.wikipedia.org/wiki/Shelterin
date created:
2012-09-27T20:18:13Z
date modified:
2024-09-05T07:17:14Z
main entity:
{"identifier":"Q3959366","url":"https://www.wikidata.org/entity/Q3959366"}
image:
fields total:
13
integrity:
15