Seyferth–Gilbert homologation

id: seyferth-gilbert-homologation-296-3496007
title: Seyferth–Gilbert homologation
text: The Seyferth–Gilbert homologation is a chemical reaction of an aryl ketone 1 with dimethyl (diazomethyl)phosphonate 2 and potassium tert-butoxide to give substituted alkynes 3. Dimethyl (diazomethyl)phosphonate 2 is often called the Seyferth–Gilbert reagent. This reaction is called a homologation because the product has exactly one additional carbon more than the starting material.
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/Seyferth%E2%80%93Gilbert_homologation
date created:
date modified: 2024-03-22T03:16:29Z
main entity: {"identifier":"Q6142429","url":"https://www.wikidata.org/entity/Q6142429"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e0/Seyferth-Gilbert_Homologation_Scheme.png","width":1017,"height":557}
fields total: 13
integrity: 15

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