Setanaxib

id: setanaxib-189-14228380
title: Setanaxib
text: Setanaxib is an experimental orally bioavailable dual inhibitor of NADPH oxidase isoforms NOX4 and NOX1. Setanaxib is a member of the pyrazolopyridine dione chemical series. The compound is the only specific NOX inhibitor that has entered into clinical trials. Setanaxib has demonstrated biological activity in a number of in vitro and in vivo animal pharmacological models including squamous cell carcinoma of the head and neck, diabetic nephropathy, retinopathy, atherosclerosis, liver fibrosis, os
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/Setanaxib
date created: 2017-05-14T13:37:45Z
date modified: 2024-09-09T08:50:05Z
main entity: {"identifier":"Q27258840","url":"https://www.wikidata.org/entity/Q27258840"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/82/Setanaxib.png","width":1473,"height":1293}
fields total: 13
integrity: 16

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