Selective estrogen receptor degrader
id:
selective-estrogen-receptor-degrader-163-12431514
title:
Selective estrogen receptor degrader
text:
A selective estrogen receptor degrader or downregulator (SERD) is a type of drug that selectively binds to the estrogen receptor (ER) and induces its degradation, and thus causes its downregulation. SERDs are used in the treatment of estrogen receptor-positive breast cancer, particularly in cases where tumors have developed resistance to other forms of endocrine therapy, such as selective estrogen receptor modulators (SERMs) or aromatase inhibitors. The mechanism of action of SERDs involves bind
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Selective_estrogen_receptor_degrader
date created:
2015-12-15T22:20:49Z
date modified:
2024-08-28T16:44:18Z
main entity:
{"identifier":"Q28208942","url":"https://www.wikidata.org/entity/Q28208942"}
image:
fields total:
13
integrity:
14