SB-271046

id: sb-271046-250-14045651
title: SB-271046
text: SB-271046 is a drug which is used in scientific research. It was one of the first selective 5-HT6 receptor antagonists to be discovered, and was found through high-throughput screening of the SmithKline Beecham Compound Bank using cloned 5-HT6 receptors as a target, with an initial lead compound being developed into SB-271046 through a structure-activity relationship (SAR) study. SB-271046 was found to be potent and selective in vitro and had good oral bioavailability in vivo, but had poor penet
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/SB-271046
date created:
date modified: 2023-07-24T18:32:05Z
main entity: {"identifier":"Q855568","url":"https://www.wikidata.org/entity/Q855568"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/76/SB-271046.svg","width":178,"height":68}
fields total: 13
integrity: 15

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