SB-236057
id:
sb-236057-301-2410131
title:
SB-236057
text:
SB-236057 is a compound which is a potent and selective inverse agonist for the serotonin receptor 5-HT1B, acting especially at 5-HT1B autoreceptors on nerve terminals. It produces a rapid increase in serotonin levels in the brain, and was originally researched as a potential antidepressant. However subsequent research found that SB-236,057 also acts as a potent teratogen, producing severe musculoskeletal birth defects when rodents were exposed to it during pregnancy. This has made it of little
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/SB-236057
date created:
date modified:
2023-01-02T13:55:21Z
main entity:
{"identifier":"Q21098842","url":"https://www.wikidata.org/entity/Q21098842"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/59/SB236057_structure.png","width":870,"height":342}
fields total:
13
integrity:
15