Saclofen
id:
saclofen-185-5037005
title:
Saclofen
text:
Saclofen is a competitive antagonist for the GABAB receptor. This drug is an analogue of the GABAB agonist baclofen. The GABAB receptor is heptahelical receptor, expressed as an obligate heterodimer, which couples to the Gi/o class of heterotrimeric G-proteins. The action of saclofen on the central nervous system is understandably modest, because G-proteins rely on an enzyme cascade to alter cell behavior while ionotropic receptors immediately change the ionic permeability of the neuronal plasma
brand slug:
wiki
category slug:
encyclopedia
description:
GABAB receptor antagonist
original url:
https://en.wikipedia.org/wiki/Saclofen
date created:
2007-05-09T23:52:19Z
date modified:
2024-09-07T17:48:26Z
main entity:
{"identifier":"Q7396879","url":"https://www.wikidata.org/entity/Q7396879"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/08/Saclofen.svg","width":520,"height":310}
fields total:
13
integrity:
16