RWJ-394674
id:
rwj-394674-249-4552065
title:
RWJ-394674
text:
RWJ-394674 is a drug that is used in scientific research. It is a potent, orally active analgesic drug that produces little respiratory depression. RWJ-394674 itself is a potent and selective agonist for δ-opioid receptors, with a Ki of 0.24 nM at δ and 72 nM at μ. However once inside the body, RWJ-394674 is dealkylated to its monodesethyl metabolite RWJ-413216, which is a potent agonist at the μ-opioid receptor and has less affinity for δ. The effect of RWJ-394674 when administered in vivo thus
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/RWJ-394674
date created:
date modified:
2024-02-08T17:40:46Z
main entity:
{"identifier":"Q7278114","url":"https://www.wikidata.org/entity/Q7278114"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/52/RWJ-394674_Structure.svg","width":512,"height":384}
fields total:
13
integrity:
15