RUNX2
id:
runx2-314-10404845
title:
RUNX2
text:
Runt-related transcription factor 2 (RUNX2) also known as core-binding factor subunit alpha-1 (CBF-alpha-1) is a protein that in humans is encoded by the RUNX2 gene. RUNX2 is a key transcription factor associated with osteoblast differentiation. It has also been suggested that Runx2 plays a cell proliferation regulatory role in cell cycle entry and exit in osteoblasts, as well as endothelial cells. Runx2 suppresses pre-osteoblast proliferation by affecting cell cycle progression in the G1 phase.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in humans
original url:
https://en.wikipedia.org/wiki/RUNX2
date created:
date modified:
2024-04-11T22:36:43Z
main entity:
{"identifier":"Q14907085","url":"https://www.wikidata.org/entity/Q14907085"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/f0/Protein_RUNX2_PDB_1cmo.png","width":773,"height":614}
fields total:
13
integrity:
15