RTI-83

id: rti-83-305-1953416
title: RTI-83
text: RTI-83 (-2β-carbomethoxy-3β-tropane) is a phenyltropane derivative which represents a rare example of an SDRI or serotonin-dopamine reuptake inhibitor, a drug which inhibits the reuptake of the neurotransmitters serotonin and dopamine, while having little or no effect on the reuptake of the related neurotransmitter noradrenaline. With a binding affinity (Ki) of 55 nM at DAT and 28.4 nM at SERT but only 4030 nM at NET, RTI-83 has reasonable selectivity for DAT/SERT over NET However, further resea
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/RTI-83
date created:
date modified: 2023-11-29T00:57:59Z
main entity: {"identifier":"Q27257583","url":"https://www.wikidata.org/entity/Q27257583"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e6/Phenyltropane_11g.svg","width":1130,"height":675}
fields total: 13
integrity: 15

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