RTI-7470-44
id:
rti-7470-44-189-11941036
title:
RTI-7470-44
text:
RTI-7470-44 is a potent and selective antagonist of the human trace amine-associated receptor 1 (TAAR1) which is used in scientific research. It was discovered in 2022 and is the first potent antagonist of the human TAAR1 to be identified, following the potent mouse TAAR1 inverse agonist EPPTB in 2009. The affinity (Ki) of RTI-7470-44 for the human TAAR1 is 0.3 nM and its inhibitory potency (IC50Tooltip half-maximal inhibitory concentration) at the receptor is 8.4 nM in vitro. It is about 90-fol
brand slug:
wiki
category slug:
encyclopedia
description:
Potent human TAAR1 antagonist
original url:
https://en.wikipedia.org/wiki/RTI-7470-44
date created:
2024-08-15T22:14:47Z
date modified:
2024-09-09T08:41:21Z
main entity:
{"identifier":"Q130130978","url":"https://www.wikidata.org/entity/Q130130978"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/8e/RTI-7470-44.svg","width":840,"height":450}
fields total:
13
integrity:
16